Imiloxan hydrochloride

Cat. No. 0986

Imiloxan hydrochloride C14H16N2O2.HCl [81167-22-8]

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Alternative Name: RS 21361

Chemical Name: 2-(1-Ethyl-2-indazoyl)methyl-1,4-benzodioxan hydrochloride

Biological Activity

A moderately potent, but highly selective α2-adrenoceptor antagonist, the only reported selective antagonist at the α2B-adrenoceptor not having potent α1-adrenoceptor antagonist activity.

Licensing Information

Sold with the permission of Roche Bioscience

Technical Data

M.Wt:
280.75
Formula:
C14H16N2O2.HCl
Solubility:
Soluble to 100 mM in water
Purity:
>98 %
Storage:
Desiccate at RT
CAS No:
81167-22-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

Michel et al (1990) Assessment of imiloxan as a selective α2B-adrenoceptor antagonist. Br.J.Pharmacol. 99 560. PMID: 1970500.

Michel and Whiting (1981) 2-(2-Imidazolylmethyl)-1,4-benzodioxans, a series of selective alpha2-adrenoceptor antagonists. Br.J.Pharmacol. 74 255P.

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Keywords: Imiloxan hydrochloride, supplier, selective, α2B-adrenoceptor, alpha2B-adrenoceptor, antagonists, α2b-adrenergic, alpha2b-adrenergic, a2-adrenoceptor, a2-adrenergic, Receptors, RS21361, Tocris Bioscience, Adrenergic α2 Receptor Antagonist products

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