Isamoltane hemifumarate

Cat. No. 0992

Isamoltane hemifumarate C16H22N2O2.C4H4O4 [874882-92-5]

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Chemical Name: 1-[(1-Methylethyl)amino]-3-[2-(1H-pyrrol-1-yl)]-propan-2-ol hemifumarate

Biological Activity

5-HT1B antagonist, approximately 30-fold selective over 5-HT1A. Also possesses affinity for β-adrenergic receptors.

Technical Data

M.Wt:
332.4
Formula:
C16H22N2O2.½C4H4O4
Solubility:
Soluble to 10 mM in water with gentle warming
Purity:
>99 %
Storage:
Desiccate at +4°C
CAS No:
874882-92-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Waldmeier et al (1988) Interactions of isamoltane (CGP 361A), an anxiolytic phenoxypropanolamine derivative, with 5-HT1 receptor subtypes in the rat brain. Naunyn Schmiedebergs Arch.Pharmacol. 337 609. PMID: 2905765.

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Keywords: Isamoltane hemifumarate, supplier, 5-HT1B, antagonist, Serotonin, Receptors, Tocris Bioscience, 5-HT1B Receptor Antagonist products

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