PD 168568 dihydrochloride
Cat. No. 3529
Chemical Name: 3-[2-[4-(3,4-dimethylphenyl)-1-pipe
Biological ActivityPotent and selective dopamine D4 receptor antagonist (Ki values are 8.8 and 1842 nM at D4 and D2 receptors respectively). Reverses amphetamine-stimulated locomotion in vivo and is orally active.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Belliotti et al (1998) Isoindolinone enantiomers having affinity for the dopamine D4 receptor. Bioorg.Med.Chem.Lett. 8 1499. PMID: 9873377.
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