Cat. No. 0708
Alternative Names: HBC, Hydroxypropyl-β-cyclodextrin
Biological ActivityThe most widely used modified cyclodextrin, the lipophilic cavity formed by 7 glucose units. Drug solubility in water is greatly enhanced by complexing with HBC.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Frijlink (1991) The effects of cyclodextrins on the disposition of intravenously injected drugs in the rat. Pharm.Res. 8 380. PMID: 2052529.
Pitha et al (1986) Hydroxypropyl-β-cyclodextrin: preparation and characterisation; effects on solubility of drugs. Int.J.Pharmacol. 29 73.
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Citations are publications that use Tocris products. Selected citations for 2-Hydroxypropyl-β-cyclodextrin include:
Johnson et al (2012) Orexin 1 receptors are a novel target to modulate panic responses and the panic brain network. Proc Natl Acad Sci U S A 107 733. PMID: 22554617.
Do you know of a great paper that uses 2-Hydroxypropyl-β-cyclodextrin from Tocris? If so please let us know.
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