Tocriscreen Kinase Inhibitor Toolbox
Cat. No. 3514
Biological ActivityA collection of 80 kinase inhibitors supplied as pre-dissolved DMSO solutions (250 μl 10 mM solution per compound).
Key Format and Product Details
- 96-well rack with Matrix storage tubes & SepraSeal caps
- Pre-dissolved in DMSO
- All compounds are biologically active
- Full chemical and biological data available
- Exceptional purity
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
on-line. Please contact Customer Service
Moujalled et al (2013) Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress. PLoS ONE 8 e67433. PMID: 23840699.
Jester et al (2010) A coiled-coil enabled split-luciferase three-hybrid system: applied toward profiling inhibitors of protein kinases. J.Am.Chem.Soc. 132 11727. PMID: 20669947.
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Citations are publications that use Tocris products. Selected citations for Tocriscreen Kinase Inhibitor Toolbox include:
Acevedo et al (2014) Phosphorylation of amyloid precursor protein at threonine 668 is essential for its copper-responsive trafficking in SH-SY5Y neuroblastoma cells. Cancer Sci 289 11007. PMID: 24610780.
FitzGerald et al (2014) A high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage response. PLoS One 9 e98891. PMID: 24902048.
Moujalled et al (2013) Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress. PLoS One 8 e67433. PMID: 23840699.
Do you know of a great paper that uses Tocriscreen Kinase Inhibitor Toolbox from Tocris? If so please let us know.
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April 1 - 5, 2017
Washington, D.C., USA