BMS 753

Cat. No. 3505

BMS 753 C21H21NO4 [215307-86-1]

Price and Availability

For BMS 753 pricing & availability please select your country from the drop down menu:
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 4-[[(2,3-Dihydro-1,1,3,3-tetramethyl-2-oxo-1H-inden-5-yl)carbonyl]amino]benzoic acid

Biological Activity

RARα-selective agonist (Ki = 2 nM).

Technical Data

Soluble to 100 mM in DMSO and to 100 mM in ethanol
>99 %
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Dilworth et al (1999) Ligand-dependent activation of transcription in vitro by retinoid acid receptor α/retinoid X receptor α heterodimers that mimics transactivation by retinoids in vivo. Proc.Natl.Acad.Sci.USA 96 1995.

Gehin et al (1999) Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists. Chem.Biol. 6 519. PMID: 10421757.

Taneja et al (1996) Cell-type and promoter-context dependent retinoic acid receptor (RAR) redundancies for RARβ2 and Hoxa-1 activation in F9 and P19 cells can be artefactually generated by gene knockouts. Proc.Natl.Acad.Sci.USA 93 6197.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for BMS 753 include:

Raverdeau et al (2012) Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis. Proc Natl Acad Sci U S A 109 16582. PMID: 23012458.

Do you know of a great paper that uses BMS 753 from Tocris? If so please let us know.

View Related Products by Product Action

Keywords: BMS 753, supplier, retinoic, acid, agonists, rara, raralpha, rar-α, selective, BMS753, Tocris Bioscience, Retinoic Acid Receptor Agonist products

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Product Guide

Our Cancer Research Guide highlights over 750 products for cancer research. Request copy or view PDF today.

divider line

Nuclear Receptors Product Listing

Nuclear Receptors Product Listing

Our Nuclear Receptors Listing highlights over 150 products for nuclear receptors. Request copy or view PDF today.

divider line

RXR and RAR Review

Written by Alexander Moise

Retinoid Receptors Scientific Review

Our Retinoid Receptor review gives a summary of retinoic acid and retinoid X receptor pharmacology, and the modulation of retinoid signaling. Request copy or view PDF today.

divider line

New Products in this Area

EC 19

Synthetic retinoid; induces differentiation of stem cells

SI-2 hydrochloride

Steroid receptor coactivator 3 (SRC-3) inhibitor

SR 0987

T cell-specific RORγ (RORγt) agonist

WAY 252623

Potent LXR agonist

SR 9009

Rev-Erbα/β agonist

SR 9238

Potent and selective LXR inverse agonist

Sign-up for new product e-alerts
divider line

LinkedIn Updates

Follow Tocris on LinkedIn

Follow us on LinkedIn!

Visit our LinkedIn page for the latest Tocris news, events and updates.