Dopamine hydrochloride

Cat. No. 3548

Dopamine hydrochloride C8H11NO2.HCl [62-31-7]

Price and Availability

For Dopamine hydrochloride pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 3,4-Dihydroxyphenethylamine hydrochloride

Biological Activity

Endogenous neurotransmitter that acts as an agonist at dopamine D1-5 receptors. Synthesized in the substantia nigra and ventral tegmental area, and is a precursor in noradrenalin and adrenalin biosynthesis. Caged dopamine is also available (Cat. No 3992).

Technical Data

M.Wt:
189.64
Formula:
C8H11NO2.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at -20°C
CAS No:
62-31-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Cools (2008) Role of dopamine in the motivational and cognitive control of behavior. Neuroscientist 14 381. PMID: 18660464.

Fitzgerald and Dinan (2008) Prolactin and dopamine: what is the connection? A review article. J.Psychopharmacol. 22 S12.

Rivonello et al (2007) Novel insights into dopamine receptor pharmacology. Eur.J.Endocrinol. 156 S13. PMID: 17413183.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for Dopamine hydrochloride include:

Brzosko et al (2015) Retroactive modulation of spike timing-dependent plasticity by dopamine. Elife 4. PMID: 26516682.

Gerhold et al (2015) Pronociceptive and Antinociceptive Effects of Buprenorphine in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude. J Neurosci 35 9580. PMID: 26134641.

Tozzi et al (2015) Endogenous 17β-estradiol is required for activity-dependent long-term potentiation in the striatum: interaction with the dopaminergic system. Front Cell Neurosci 9 192. PMID: 26074768.

Zhang et al (2013) Sucrose produces withdrawal and dopamine-sensitive reinforcing effects in planarians. Physiol Behav 112-113 8. PMID: 23415661.

O'Keeffe et al (2009) Dopamine-induced proliferation of adult neural precursor cells in the mammalian subventricular zone is mediated through EGF. Proc Natl Acad Sci U S A 106 8754. PMID: 19433789.

Do you know of a great paper that uses Dopamine hydrochloride from Tocris? If so please let us know.show all ▼show less ▲

View Related Products by Product Action

Keywords: Dopamine hydrochloride, supplier, Endogenous, agonists, dopamine, D1, receptors, Dopamine, D2, D3, Non-Selective, Receptors, D5, dopaminergic, TAAR1, Tocris Bioscience, D1 and D5 Receptor Agonist products

Quick Order

Find multiple products by catalog number

divider line

Neurodegeneration Research Product Guide

Neurodegeneration Product Guide

Our Neurodegeneration guide highlights over 275 products for neurodegeneration research. Request copy or view PDF today.

divider line

GPCR Product Listing

GPCR Product Listing

Highlights over 450 products for GPCRs Request copy or view PDF today.

divider line

Dopamine Review

Written by P. Strange & K.Neve

Dopamine Receptors Scientific Review

Our Dopamine receptors review gives an overview of the dopamine receptor subtypes, and the receptor agonists and antagonists used to study them. Request copy or view PDF today.

divider line

Regulation of Vascular Reactivity by GPCRs

Written by J.J. Maguire and A.P. Davenport

Cardiovascular Life Science Poster

Our Cardiovascular poster highlights the key G protein-coupled receptors involved in the regulation of vascular reactivity. Request copy today.

divider line

Antidepressants - Current and Future Targets

Written by P. Skolnich et al

Depression Life Science Poster

Our Depression poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder. Request copy or view PDF today.

divider line

Parkinson's disease: Neurobiology and Therapeutic Strategies

Written by Anthony H.V. Schapira

Parkinson's Life Science Poster

Our Parkinson's disease (PD) poster summarizes the neurobiology of the disease, and highlights current therapeutic treatments for symptomatic PD. Request copy or view PDF today.

divider line

Mechanisms of Addiction

Addiction Life Science Poster

Written by Prof David Nutt, this poster summarizes the brain circuits and neurotransmitter systems that are affected by the main classes of addictive drugs. Request copy or view PDF today.

divider line

New Products in this Area

SKF 82958 hydrobromide

D1 agonist

Droperidol

D2 receptor antagonist

Sign-up for new product e-alerts
divider line

Bio-Techne Events

Neuroscience 2016

Neuroscience 2016

November 12 - 16, 2016

San Diego, CA, USA

Booth: 3217