Cat. No. 1241
Chemical Name: cis-4-[Phosphomethyl]-piperidine-2-
Biological ActivityPotent, competitive NMDA receptor antagonist. Anticonvulsant and neuroprotective. Also available as part of the Mixed NMDA Receptor Tocriset™.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Perez-Pinzon et al (1995) Correlation of CGS 19755 neuroprotection against in vivo excitotoxicity and focal cerebral ischemia. J.Cereb.Blood Flow Metab. 15 865. PMID: 7673380.
Bennett et al (1989) Behavioral pharmacological profile of CGS 19755, a competitive antagonist at N-methyl-D-aspartate receptors. J.Pharmacol.Exp.Ther. 250 454. PMID: 2547931.
Lehmann et al (1988) CGS 19755, a selective and competitive N-methyl-D-aspartate-type excitatory amino acid receptor antagonist. J.Pharmacol.Exp.Ther. 246 65. PMID: 2899170.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products. Selected citations for CGS 19755 include:
Pedrazzi et al (2012) Potentiation of NMDA receptor-dependent cell responses by extracellular high mobility group box 1 protein. PLoS One 7 e44518. PMID: 22952988.
Do you know of a great paper that uses CGS 19755 from Tocris? If so please let us know.
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Keywords: CGS 19755, supplier, Potent, competitive, NMDA, antagonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGlur, Ionotropic, CGS19755, Tocris Bioscience, NMDA Receptor Antagonist products
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