Tris DBA

Cat. No. 3416

Tris DBA C51H42O3Pd2 [51364-51-3]

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Chemical Name: Tris(dibenzylideneacetone) dipalladium

Biological Activity

N-myristoyltransferase-1 (NMT-1) inhibitor that prevents activation of MAPK, PI 3-K and STAT3 signaling pathways. Exhibits antiproliferative activity against melanoma cells in vitro and in vivo. Also used as a cyclization catalyst.

Technical Data

M.Wt:
915.73
Formula:
C51H42O3Pd2
Solubility:
Soluble to 11 mM in DMSO
Storage:
Store at RT
CAS No:
51364-51-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Bhandarkar et al (2008) Tris(Dibenzylideneacetone) dipalladium, a N-myristoyltransferase-1 inhibitor, is effective against melanoma growth in vitro and in vivo. Clin.Cancer Res. 14 5743. PMID: 18794083.

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Keywords: Tris DBA, supplier, N-myristoyltransferase-1, inhibitors, inhibits, antiproliferative, Transferases, TrisDBA, Tocris Bioscience, Other Transferase Inhibitor products

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