Cat. No. 3411
Alternative Name: BMS 649
Chemical Name: 4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-te
Biological ActivityPan retinoid X receptor (RXR) agonist that is devoid of any RAR activity.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Zhou et al (2010) Retinoid X receptor agonists inhibit phorbol-12-myristate-13-acetate (PMA)-induced differentiation of monocytic THP-1 cells into macrophages. Mol.Cell.Biochem. 335 283. PMID: 19784811.
Benoit et al (1999) RAR-independent RXR signaling induces t(15;17) leukemia cell maturation. EMBO J. 18 7011. PMID: 10601023.
Chiba et al (1997) Distinct retinoid X receptor-retinoic acid receptor heterodimers are differentially involved in the control of expression of retinoid target genes in F9 embryonal carcinoma cells. Mol.Cell.Biol. 17 3013. PMID: 9154799.
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Citations are publications that use Tocris products.
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Keywords: SR 11237, supplier, SR11237, BMS649, retinoid, X, receptors, agonist, pan, RXR, RXRalpha, RTXRbeta, RXRgamma, RXRg, RXRa, RXRb, RXRα, RXRβ, RXRγ, Tocris Bioscience, Retinoid X Receptor Agonist products
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