2-Methylthioadenosine triphosphate tetrasodium salt

Cat. No. 1062

2-Methylthioadenosine triphosphate tetrasodium salt C11H14N5Na4O13P3S [100020-57-3]

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Alternative Name: 2-Methylthio-ATP

Chemical Name: 2-Methylthioadenosine-5'-triphosphate tetrasodium salt

Biological Activity

P2 purinoceptor agonist.

Technical Data

Soluble to 100 mM in water
Desiccate at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
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References are publications that support the products' biological activity.

Khakh et al (2001) International Union of Pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits. Pharmacol.Rev. 53 107. PMID: 11171941.

McMurray et al (1998) Purinoceptor subtypes mediating contraction and relaxation of marmoset urinary bladder smooth muscle. Br.J.Pharmacol. 123 1579. PMID: 9605564.

Burnstock et al (1983) Studies on the stereoselectivity of the P2-purinoreceptor. Br.J.Pharmacol. 79 907. PMID: 6317121.

Cusack et al (1982) Specific but non-competitive inhibition by 2-alkylthioanalogues of adenosine 5'-monophosphate and adenosine 5'-triphosphate of human platelet aggregation induced by adenosine 5'-diphosphate. Br.J.Pharmacol. 75 397. PMID: 7186826.

If you know of a relevant reference for 2-Methylthioadenosine triphosphate tetrasodium salt please let us know.

Citations are publications that use Tocris products. Selected citations for 2-Methylthioadenosine triphosphate tetrasodium salt include:

Rahbar et al (2016) Purinergic and Cholinergic Drugs Mediate Hyperventilation in Zebrafish: Evidence from a Novel Chemical Screen. Nature 11 e0154261. PMID: 27100625.

Zhang et al (2014) Agonist-bound structure of the human P2Y12 receptor. Med J Islam Repub Iran 509 119. PMID: 24784220.

Do you know of a great paper that uses 2-Methylthioadenosine triphosphate tetrasodium salt from Tocris? If so please let us know.

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Keywords: 2-Methylthioadenosine triphosphate tetrasodium salt, supplier, P2, purinergic, agonists, P2X, Receptors, Purinergic, P2Y, purinoceptors, Tocris Bioscience, Purinergic (P2X) Receptor Agonist products

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