Methysergide maleate

Cat. No. 1064

Methysergide maleate C21H27N3O2.C4H4O4 [129-49-7]

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Chemical Name: [8β(S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-1,6-dimethylergoline-8-carboxamide maleate

Biological Activity

Mixed 5-HT1/5-HT2 receptor antagonist.

Technical Data

M.Wt:
469.54
Formula:
C21H27N3O2.C4H4O4
Solubility:
Soluble to 10 mM in water with gentle warming
Purity:
>99 %
Storage:
Store at RT
CAS No:
129-49-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Hoyer et al (1994) VII. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol.Rev. 46 157. PMID: 7938165.

Merck Index 12 6217.

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Citations are publications that use Tocris products. Selected citations for Methysergide maleate include:

Williams et al (2012) Reduced levels of serotonin 2A receptors underlie resistance of Egr3-deficient mice to locomotor suppression by clozapine. Neuropsychopharmacology 37 2285. PMID: 22692564.

Murray et al (2010) Recovery of motoneuron and locomotor function after spinal cord injury depends on constitutive activity in 5-HT2C receptors. Nat Med 16 694. PMID: 20512126.

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Keywords: Methysergide maleate, supplier, 5-HT1, 5-HT2, antagonists, Non-Selective, 5-Hydroxytryptamine, Receptors, Serotonin, Tocris Bioscience, Non-selective 5-HT Antagonist products

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