Cat. No. 1064
Chemical Name: [8β(S)]-9,10-Didehydro-N-[1-(hydroxy
Biological ActivityMixed 5-HT1/5-HT2 receptor antagonist.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Hoyer et al (1994) VII. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol.Rev. 46 157. PMID: 7938165.
Merck Index 12 6217.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products. Selected citations for Methysergide maleate include:
Williams et al (2012) Reduced levels of serotonin 2A receptors underlie resistance of Egr3-deficient mice to locomotor suppression by clozapine. Neuropsychopharmacology 37 2285. PMID: 22692564.
Murray et al (2010) Recovery of motoneuron and locomotor function after spinal cord injury depends on constitutive activity in 5-HT2C receptors. Nat Med 16 694. PMID: 20512126.
Do you know of a great paper that uses Methysergide maleate from Tocris? If so please let us know.
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Keywords: Methysergide maleate, supplier, 5-HT1, 5-HT2, antagonists, Non-Selective, 5-Hydroxytryptamine, Receptors, Serotonin, Tocris Bioscience, Non-selective 5-HT Antagonist products
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October 30 - November 3, 2016
Boston, MA, USA