Myelin Basic Protein (87-99)
Cat. No. 3399
Biological ActivityEncephalitogenic peptide that induces T cell proliferation with Th1 polarization in the CNS. Major antigenic component implicated in the pathophysiology of multiple sclerosis.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Deraos et al (2008) Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP87-99) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: Implications in triggering disease. J.Med.Chem. 51 7834. PMID: 19053745.
Hofstetter et al (2005) Does the frequency and avidity spectrum of the neuroantigen-specific T cells in the blood mirror the autoimmune process in the central nervous system of mice undergoing experimental allergic encephalomyelitis? J.Immunol. 22 4598.
Jones et al (1992) The synthetic 87-99 peptide of myelin basic protein is encelphalitogenic in Buffalo rats. J.Neuroimmunol. 37 203. PMID: 1373154.
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Keywords: Myelin Basic Protein (87-99), supplier, antigenic, component, implicated, pathophysiology, multiple, sclerosis, Encephalitogenic, peptide, Neuronal, Metabolism, Tocris Bioscience, Neuronal Metabolism products
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