Cat. No. 3393
Biological ActivityReversed amino acid sequence control peptide for TFLLR-NH2 (Cat. No. 1464), a PAR1 selective agonist that significantly increases nociceptive threshold.
(Modifications: Thr-5 = C-terminal amide)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Buresi et al (2004) Activation of proteinase-activated receptor-1 inhibits neurally evoked chloride secretion in the mouse colon in vitro. Am.J.Physiol.Gastrointest.Liver Physiol. 288 G337. PMID: 15345469.
Fang et al (2003) Thrombin inhibits NMDA-mediated nociceptive activity in the mouse: possible mediation by endothelin. J.Physiol. 549 903. PMID: 12717003.
Asfaha et al (2002) Proteinase-activated receptor-1 agonists attenuate nociception in response to noxious stimuli. Br.J.Pharmacol. 135 1101. PMID: 11877315.
If you know of a relevant reference for RLLFT-NH2 please let us know.
Citations are publications that use Tocris products. Selected citations for RLLFT-NH2 include:
Chen et al (2012) Thrombin activity associated with neuronal damage during acute focal ischemia. J Neurosci 32 7622. PMID: 22649241.
Do you know of a great paper that uses RLLFT-NH2 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: RLLFT-NH2, supplier, Control, peptide, TFLLR-NH2, PAR, Receptors, Protease-Activated, proteinase-activated, Tocris Bioscience, Protease-Activated Receptor Agonist products
Find multiple products by catalog number
New Products in this Area
Negative control for ELA-32 (Cat.No.6291).ELA-32 (human)
Potent, high affinity apelin receptor agonist; stimulates angiogenesisParathyroid hormone (1-34) (bovine)
Parathyroid hormone (PTH) receptor agonist.Parathyroid hormone (1-34) (rat)
Parathyroid hormone (PTH) receptor agonistPeptide YY (3-36) human
NPY Y2 receptor agonistELA-14 negative control
Negative control for ELA-14 (Cat.No.6293).ELA-14 (human)
Potent apelin (APJ) receptor agonistRetrobradykinin
Reverse analog of BradykininTASP 0390325
Potent and selective V1B receptor antagonist; orally bioavailable
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.