PNU 177864 hydrochloride
Cat. No. 3355
Chemical Name: N-[4-[2-(Propylamino)ethyl)phenyl]-
Biological ActivityHighly selective dopamine D3 receptor antagonist. Induces phospholipidosis and exhibits antischizophrenic activity in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Rudmann et al (2004) Epididymal and systemic phospholipidosis in rats and dogs treated with dopamine D3 selective antagonist PNU-177864. Toxicol.Pathol. 32 326. PMID: 15204974.
Vonderfecht et al (2004) Myopathy related to administration of a cationic amphiphilic drug and the use of multidose drug distribution analysis to predict its occurrence. Toxicol.Pathol. 32 318. PMID: 15204973.
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