Clofibrate

Cat. No. 0824

Clofibrate C12H15ClO3 [637-07-0]

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Chemical Name: Ethyl 2-(4-chlorophenoxy)-2-methylpropionate

Biological Activity

PPAR agonist (EC50 values are 50, 500 and > 100 μM at PPARα, PPARγ and PPARδ respectively). Antihyperlipoproteinemic.

Technical Data

M.Wt:
242.7017
Formula:
C12H15ClO3
Solubility:
Soluble to 100 mM in DMSO
Storage:
Store at RT
CAS No:
637-07-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Bishop-Bailey (2000) Peroxisome proliferator-activated receptors in the cardiovascular system. Br.J.Pharmacol. 129 823. PMID: 10696077.

Willson et al (2000) The PPARs: from orphan receptors to drug discovery. J.Med.Chem. 43 527. PMID: 10691680.

Shepherd (1993) Mechanism of action of fibrates. Postgrad.Med.J. 69 S34. PMID: 8497455.

Merck Index 12 2437.

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Keywords: Clofibrate, supplier, PPAR, agonists, Non-Selective, Peroxisome, Proliferator-activating, Receptors, Tocris Bioscience, Non-selective PPAR Agonist products

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