Cat. No. 0824
Chemical Name: Ethyl 2-(4-chlorophenoxy)-2-methylpropion
Biological ActivityPPAR agonist (EC50 values are 50, 500 and > 100 μM at PPARα, PPARγ and PPARδ respectively). Antihyperlipoproteinemic.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Bishop-Bailey (2000) Peroxisome proliferator-activated receptors in the cardiovascular system. Br.J.Pharmacol. 129 823. PMID: 10696077.
Willson et al (2000) The PPARs: from orphan receptors to drug discovery. J.Med.Chem. 43 527. PMID: 10691680.
Shepherd (1993) Mechanism of action of fibrates. Postgrad.Med.J. 69 S34. PMID: 8497455.
Merck Index 12 2437.
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Citations are publications that use Tocris products.
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Keywords: Clofibrate, supplier, PPAR, agonists, Non-Selective, Peroxisome, Proliferator-activating, Receptors, Tocris Bioscience, Non-selective PPAR Agonist products
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November 8 - 10, 2017