Cat. No. 0888
Chemical Name: 2-(2-Cyclopropylphenoxymethyl)imida
Biological ActivitySelective α1 agonist. Also available as part of the α1-Adrenoceptor Tocriset™ and Mixed Adrenergic Tocriset™.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Le Rouzic et al (1995) Binding of [3H]cirazoline to an imidazoline site in rat brain and kidney membranes. Eur.J.Pharmacol. 278 261. PMID: 7589165.
Wikberg and Uklen (1990) Further characterisation of the guinea pig cerebral cortex idazoxan receptor: solubilization, distinction from the imidazole site, and demonstration of cirazoline as an idazoxan receptor-selective drug. J.Neurochem. 55 192. PMID: 1972387.
Gellai and Ruffolo (1987) Renal effects of selective alpha-1 and alpha-2 adrenoreceptor agonists in conscious normotensive rats. J.Pharmacol.Exp.Ther. 240 723. PMID: 2882013.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products. Selected citations for Cirazoline hydrochloride include:
Maupoil et al (2007) Ectopic activity in the rat pulmonary vein can arise from simultaneous activation of alpha1- and beta1-adrenoceptors. Br J Pharmacol 150 899. PMID: 17325650.
Do you know of a great paper that uses Cirazoline hydrochloride from Tocris? If so please let us know.
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Keywords: Cirazoline hydrochloride, supplier, Selective, α1, α1-adrenoceptor, alpha1-adrenoceptor, α1-adrenergic, alpha1-adrenergic, a1-adrenoceptor, a1-adrenergic, agonists, Imidazoline, ligands, Receptors, General, Imidazolines, Tocris Bioscience, Adrenergic α1 Receptor Agonist products
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Selective, high affinity, non-competitive α1A adrenoceptor antagonist
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