CART (62-76) (rat, human)

Cat. No. 3339

CART (62-76) (rat, human) Tyr-Gly-Gln-Val-Pro-Met-Cys-Asp-Ala-Gly-Glu-Gln-Cys-Ala-Val

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Alternative Name: Cocaine and amphetamine-regulated transcript (62-76) (rat, human)

Biological Activity

Cocaine- and amphetamine-regulated transcript (CART) peptide fragment that inhibits food intake. Attenuates NPY-induced feeding and decreases food intake in food-restricted goldfish, and induces anxiogenic-like effects in elevated plus-maze test in rats. Modulates the activity of striatal noradrenergic, and corticostrial and hypothalamic serotoninergic systems, with no major effect on dopaminergic pathways in rat brain.

Technical Data

M.Wt:
1570.77
Formula:
C64H99N17O23S3
Sequence:
YGQVPMCDAGEQCAV
Solubility:
Soluble to 1 mg/ml in 20% acetonitrile / water
Storage:
Store at -20°C
CAS No:
210978-19-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Colombo et al (2003) Effects of ghrelin and other neuropeptides (CART, MCH, orexin A and B, and GLP-1) on release of insulin from isolated rat islets. Pancreas 27 161. PMID: 12883265.

Vaarmann and Kask (2001) Cocaine and amphetamine-regulated transcript peptide (CART62-76)-induced changes in regional monoamine levels in rat brain. Neuropeptides 35 292. PMID: 12030814.

Volkoff and Peter (2000) Effects of CART peptides on food consumption, feeding and associated behaviors in the goldfish, Carassius auratus: actions on neuropeptide Y- and orexin A-induced feeding. Brain Res. 887 125. PMID: 11134597.

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Keywords: CART (62-76) (rat, human), supplier, Neuromodulating, neuropeptide, fragment, inhibits, inhibitors, food, intake, vivo, Peptide, Receptor, Receptors, Cocaine, amphetamine-regulated, transcript, CART, peptide, amphetamine, neuropeptides, cart62-76, Tocris Bioscience, Other Peptide Receptor products

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