CART (62-76) (rat, human)
Cat. No. 3339
Alternative Name: Cocaine and amphetamine-regulated transcript (62-76) (rat, human)
Biological ActivityCocaine- and amphetamine-regulated transcript (CART) peptide fragment that inhibits food intake. Attenuates NPY-induced feeding and decreases food intake in food-restricted goldfish, and induces anxiogenic-like effects in elevated plus-maze test in rats. Modulates the activity of striatal noradrenergic, and corticostrial and hypothalamic serotoninergic systems, with no major effect on dopaminergic pathways in rat brain.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Colombo et al (2003) Effects of ghrelin and other neuropeptides (CART, MCH, orexin A and B, and GLP-1) on release of insulin from isolated rat islets. Pancreas 27 161. PMID: 12883265.
Vaarmann and Kask (2001) Cocaine and amphetamine-regulated transcript peptide (CART62-76)-induced changes in regional monoamine levels in rat brain. Neuropeptides 35 292. PMID: 12030814.
Volkoff and Peter (2000) Effects of CART peptides on food consumption, feeding and associated behaviors in the goldfish, Carassius auratus: actions on neuropeptide Y- and orexin A-induced feeding. Brain Res. 887 125. PMID: 11134597.
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Keywords: CART (62-76) (rat, human), supplier, Neuromodulating, neuropeptide, fragment, inhibits, inhibitors, food, intake, vivo, Peptide, Receptor, Receptors, Cocaine, amphetamine-regulated, transcript, CART, peptide, amphetamine, neuropeptides, cart62-76, Tocris Bioscience, Other Peptide Receptor products
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