CART (55-102) (rat)

Cat. No. 3337

CART (55-102) (rat) Ile-Pro-Ile-Tyr-Glu-Lys-Lys-Tyr-Gly-Gln-Val-Pro-Met-Cys-Asp-Ala-Gly-Glu-Gln-Cys-Ala-Val-Arg-Lys-Gly-Ala-Arg-Ile-Gly-Lys-Leu-Cys-Asp-Cys-Pro-Arg-Gly-Thr-Ser-Cys-Asn-Ser-Phe-Leu-Leu-Lys-Cys-Leu

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Biological Activity

Cocaine- and amphetamine-regulated transcript (CART) with potent appetite-suppressing activity. Satiety factor; inhibits normal and starvation-induced feeding. Closely related to the actions of leptin and neuropeptide Y; blocks the neuropeptide Y-induced feeding response. Induces anxiety and stress behavior in rodents.

Technical Data

M.Wt:
5259.21
Formula:
C226H367N65O65S7
Sequence:
IPIYEKKYGQVPMCDAGEQCAVRKGARIGKLCDCPRGTSCNSFLLKCL

(Modifications: Disulfide bridge between 14 - 32, 20 - 40, 34 - 47)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Store at -20°C
CAS No:
209615-79-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Chaki et al (2003) Cocaine- and amphetamine-regulated transcript peptide produces anxiety-like behavior in rodents. Eur.J.Pharmacol. 464 49. PMID: 12600694.

Ludvigsen et al (2001) Solution structure of the satiety factor, CART, reveals new functionality of a well-known fold. Biochemistry 40 9082. PMID: 11478874.

Thim et al (1998) CART, a new anorectic peptide. Int.J.Biochem.Cell Biol. 30 1281. PMID: 9924797.

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Keywords: CART (55-102) (rat), supplier, CART, rat, peptide, 55-102, satiety, factor, inhibits, feeding, supresses, appetite, Tocris Bioscience, Other Peptide Receptor products

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