CART (55-102) (rat)
Cat. No. 3337
Biological ActivityCocaine- and amphetamine-regulated transcript (CART) with potent appetite-suppressing activity. Satiety factor; inhibits normal and starvation-induced feeding. Closely related to the actions of leptin and neuropeptide Y; blocks the neuropeptide Y-induced feeding response. Induces anxiety and stress behavior in rodents.
(Modifications: Disulfide bridge between 14 - 32, 20 - 40, 34 - 47)
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Chaki et al (2003) Cocaine- and amphetamine-regulated transcript peptide produces anxiety-like behavior in rodents. Eur.J.Pharmacol. 464 49. PMID: 12600694.
Ludvigsen et al (2001) Solution structure of the satiety factor, CART, reveals new functionality of a well-known fold. Biochemistry 40 9082. PMID: 11478874.
Thim et al (1998) CART, a new anorectic peptide. Int.J.Biochem.Cell Biol. 30 1281. PMID: 9924797.
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Keywords: CART (55-102) (rat), supplier, CART, rat, peptide, 55-102, satiety, factor, inhibits, feeding, supresses, appetite, Tocris Bioscience, Other Peptide Receptor products
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