Cat. No. 3325
Chemical Name: N-[1-(2-Fluorophenyl)-3-phenyl-1H-p
Biological ActivityMetabotropic glutamate receptor 5 (mGlu5) positive allosteric modulator (EC50 = 9.6 nM, Ki = 156 nM at rat mGlu5).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
de Paulis et al (2006) Substituent effects of N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides on positive allosteric modulation of the metabotropic glutamate-5 receptor in rat cortical astrocytes. J.Med.Chem. 49 3332. PMID: 16722652.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses VU 1545 from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: VU 1545, supplier, mGlu5, mGluR5, positive, allosteric, modulators, mGlur, Group, I, Receptors, Glutamate, Metabotropic, VU1545, Tocris Bioscience, Glutamate (Metabotropic) Group I Receptor Modulator products