CD 3254

Cat. No. 3302

CD 3254 C24H28O3 [196961-43-0]

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Chemical Name: 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoic acid

Biological Activity

Selective RXRα agonist; exhibits no activity at RARα, RARβ or RARγ receptors.

Technical Data

M.Wt:
364.48
Formula:
C24H28O3
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
>97 %
Storage:
Store at -20°C
CAS No:
196961-43-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

le Maire et al (2009) Activation of RXR-PPAR heterodimers by organotin environmental endocrine disruptors. EMBO.Rep. 10 367. PMID: 19270714.

Nahoum et al (2007) Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function. Proc.Natl.Acad.Sci. 104 17323.

Pogenberg et al (2005) Characterization of the interaction between retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers and transcriptional coactivators through structural and fluorescence anisotropy studies. J.Biol.Chem. 280 1625. PMID: 15528208.

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Keywords: CD 3254, supplier, Potent, selective, RXR, agonists, CD3254, aRXR, alphaRXR, αRXR, retinoid, X, receptor, Tocris Bioscience, Retinoid X Receptor Agonist products

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