Cat. No. 3302
Chemical Name: 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-
Biological ActivitySelective RXRα agonist; exhibits no activity at RARα, RARβ or RARγ receptors.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
le Maire et al (2009) Activation of RXR-PPAR heterodimers by organotin environmental endocrine disruptors. EMBO.Rep. 10 367. PMID: 19270714.
Nahoum et al (2007) Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function. Proc.Natl.Acad.Sci. 104 17323.
Pogenberg et al (2005) Characterization of the interaction between retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers and transcriptional coactivators through structural and fluorescence anisotropy studies. J.Biol.Chem. 280 1625. PMID: 15528208.
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Citations are publications that use Tocris products.
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Keywords: CD 3254, supplier, Potent, selective, RXR, agonists, CD3254, aRXR, alphaRXR, αRXR, retinoid, X, receptor, Tocris Bioscience, Retinoid X Receptor Agonist products
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