3-CPMT

Cat. No. 0917

3-CPMT C21H24ClNO.HCl [14008-79-8]

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Chemical Name: 3α-[(4-Chlorophenyl)phenylmethoxy] tropane hydrochloride

Biological Activity

This cocaine analog binds with high affinity to the dopamine transporter (Ki = 30 nM) and blocks re-uptake of dopamine. However, it is a weak psychomotor stimulant and does not substitute for cocaine in addicted rats.

Technical Data

M.Wt:
378.34
Formula:
C21H24ClNO.HCl
Solubility:
Soluble to 75 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
14008-79-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Newman et al (1995) Novel 4'-substituted and 4'4"-disubstituted 3α-(diphenylmethoxy)tropane analogs as potent and selective dopamine uptake inhibitors. J.Med.Chem. 38 3933. PMID: 7562926.

Newman et al (1994) Novel 3α-(diphenylmethoxy)tropane analogs: potent dopamine uptake inhibitors without cocaine-like behavioural profiles. J.Med.Chem. 37 2258. PMID: 8057273.

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Keywords: 3-CPMT, supplier, Dopamine, reuptake, inhibitors, inhibits, DAT, Transporters, Monoamine, Neurotransmitter, Tocris Bioscience, Dopamine Transporter Inhibitor products

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