Rec 15/2615 dihydrochloride
Cat. No. 3284
Chemical Name: 1-(4-Amino-6,7-dimethoxy-2-quinazol
Biological ActivitySelective α1B-adrenoceptor antagonist (Ki values are 0.3, 1.9 and 2.6 nM at human α1B, α1A and α1D receptors respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Morston et al (2007) α1A-adrenoceptors mediate contractions to phenylephrine in rabbit penile arteries. Br.J.Pharmacol. 150 112. PMID: 17115072.
Bremner et al (2000) Ligand design for α1 adrenoceptor subtype selective antagonist. Bioorg.Med.Chem. 8 201. PMID: 10968279.
Testa et al (1997) Pharmacological characterization of the uroselective alpha-1 antagonist Rec 15/2739 (SB 216469): Role of the alpha-1L adrenoceptor in tissue selectivity, part II. J.Pharmacol.Exp.Ther. 281 1284. PMID: 9190864.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Rec 15/2615 dihydrochloride from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Rec 15/2615 dihydrochloride, supplier, Selective, α1B-adrenoceptor, alpha1B-adrenoceptor, a1b-adrenoceptor, antagonists, α1b-adrenergic, alpha1b-adrenergic, a1b-adrenergic, Receptors, Rec15/2615, dihydrochloride, Tocris Bioscience, Adrenergic α1 Receptor Antagonist products
Find multiple products by catalog number
One Day Symposium
March 1, 2017
Amsterdam, The Netherlands