Cat. No. 3276
Chemical Name: (±)-5-Ethyl-3-methyl-5-phenyl-2,4-im
Biological ActivityCYP2C19 and CYP2B6 substrate. Anticonvulsant.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Foti et al (2008) CYP2C19 inhibition: the impact of substrate probe selection on in vitro inhibition profiles. Drug Meta. Dispos. 36 523. PMID: 18048485.
Tamminga et al (2001) Mephenytoin as a probe for CYP2C19 phenotyping: effect of sample storage, intra-individual reproducibility and occurrence of adverse events. Br.J.Clin.Pharmacol. 51 471. PMID: 11422005.
Knabe and Wunn (1980) Racemic and optically active hydantoins from disubstituted cyanoacetic acids. Arch.Pharmacol. 313 53.
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Citations are publications that use Tocris products.
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Keywords: Mephenytoin, supplier, CYP2C19, Anticonvulsant, Cytochrome, P450, Tocris Bioscience, Cytochrome P450 Substrate products
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