Cat. No. 3248
Chemical Name: cis-2-[[(3,5-Dichlorophenyl)amino]c
Biological ActivityPotent, positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50 = 798 and 693 nM at human and rat mGlu4 receptors respectively). Active in in vivo models of Parkinson's disease following i.c.v. administration. Also available as sodium salt (Cat. No. 3311).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Niswender et al (2008) Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4. Mol.Pharmacol. 74 1345. PMID: 18664603.
If you know of a relevant reference for VU 0155041 please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses VU 0155041 from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: VU 0155041, supplier, Potent, positive, allosteric, mGlu4, mGluR4, agonists, mGlur, Group, III, Receptors, Glutamate, Metabotropic, VU0155041, Tocris Bioscience, Glutamate (Metabotropic) Group III Receptor Agonist products