TCS PrP Inhibitor 13
Cat. No. 3238
Chemical Name: 2,4-Dihydro-5-(4-nitrophenyl)-2-phe
Biological ActivityAntiprion agent. Potently inhibits protease-resistant prion protein (PrP-res) accumulation in two types of prion-infected mouse neuroblastoma (N2a) cell lines (IC50 = 3 nM).
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Kimata et al (2007) New series of antiprion compounds: pyrazolone derivatives have potent activity of inhibiting protease-resistant prion protein accumulation. J.Med.Chem. 50 5053. PMID: 17850126.
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Keywords: TCS PrP Inhibitor 13, supplier, Antiprion, agent, potently, inhibits, inhibitors, PrP-res, accumulation, Prion, Protein, Neuronal, Metabolism, TCSPrP, Inhibitor13, Tocris Bioscience, Neuronal Metabolism products
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