BIM 23042

Cat. No. 3237

BIM 23042 D-Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-Nal-NH2

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Biological Activity

Selective neuromedin B receptor (NMB-R, BB1) antagonist (Ki values are 216 and 18,264 nM for BB1 and BB2 receptors respectively). Displays no activity at a range of other receptors.

Technical Data

M.Wt:
1192.46
Formula:
C63H73N11O9S2
Sequence:
XCYWKVCX

(Modifications: Disulfide bridge between 2 - 7, X-1 = D-Nal, Trp-4 = D-Trp, X-8 = Nal & C-terminal amide)

Solubility:
Soluble to 1 mg/ml in 0.1% acetic acid
Storage:
Desiccate at -20°C
CAS No:
111857-96-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Certificate of Analysis / Product Datasheet
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Milusheva et al (1998) Role of different bombesin receptor subtypes mediating contractile activity in cat upper gastrointestinal tract. Peptides 19 549. PMID: 9533644.

Ryan et al (1996) Pharmacological profiles of two bombesin analogues in cells transfected with human neuromedin B receptors. Eur.J.Pharmacol. 306 307. PMID: 8813645.

Orbuch et al (1993) Discovery of a novel class of neuromedin B receptor antagonists, substituted somatostatin analogues. Mol.Pharmacol. 44 841. PMID: 7901752.

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Keywords: BIM 23042, supplier, Selective, neuromedin, B, receptor, antagonists, NMB-R, BB1, NMB-Preferring, Neuromedin, B-Preferring, Bombesin, BIM23042, Tocris Bioscience, Bombesin Receptor Antagonist products

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