Lys-Bradykinin

Cat. No. 3227

Lys-Bradykinin Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg

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Alternative Name: Kallidin

Biological Activity

Endogenous bradykinin receptor agonist that displays some selectivity for the B2 receptor (Ki values are 2.54 and 0.63 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces peripheral vascular resistance in vivo. Twice as potent as bradykinin (Cat No. 3004) in vivo.

Technical Data

M.Wt:
1188.39
Formula:
C56H85N17O12
Sequence:
KRPPGFSPFR
Solubility:
Soluble to 5 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
342-10-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Leeb-Lundberg et al (2005) International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol.Rev. 57 27. PMID: 15734727.

Regoli et al (2001) Classification of kinin receptors. Biol.Chem. 382 31. PMID: 11258668.

Regoli and Barabe (1980) Pharmacology of bradykinin and related kinins. Pharmacol.Rev. 32 1. PMID: 7015371.

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Keywords: Lys-Bradykinin, supplier, Potent, bradykinin, receptor, agonists, B2, B1, Receptors, Tocris Bioscience, Bradykinin Receptor Agonist products

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