Cat. No. 3225
Alternative Name: Des-Arg10-Kallidin
Biological ActivityEndogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces peripheral vascular resistance in vivo. 16-fold more potent than [Des-Arg9]-Bradykinin (Cat No. 3005).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Leeb-Lundberg et al (2005) International union of pharmacology. LV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol.Rev. 57 27. PMID: 15734727.
Regoli et al (2001) Classification of kinin receptors. Biol.Chem. 382 31. PMID: 11258668.
Drapeau et al (1991) Hypotensive effects of Lys-des-Arg9-Bradykinin and metabolically protected agonists of B1 receptors for kinins. J.Pharmacol.Exp.Ther. 259 997. PMID: 1662280.
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Keywords: Lys-[Des-Arg9]Bradykinin, supplier, Selective, B1, agonists, Receptors, Bradykinin, Tocris Bioscience, Bradykinin Receptor Agonist products
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