Cat. No. 3225
Alternative Name: Des-Arg10-Kallidin
Biological ActivityEndogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces peripheral vascular resistance in vivo. 16-fold more potent than [Des-Arg9]-Bradykinin (Cat No. 3005).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Leeb-Lundberg et al (2005) International union of pharmacology. LV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol.Rev. 57 27. PMID: 15734727.
Regoli et al (2001) Classification of kinin receptors. Biol.Chem. 382 31. PMID: 11258668.
Drapeau et al (1991) Hypotensive effects of Lys-des-Arg9-Bradykinin and metabolically protected agonists of B1 receptors for kinins. J.Pharmacol.Exp.Ther. 259 997. PMID: 1662280.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Lys-[Des-Arg9]Bradykinin from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Lys-[Des-Arg9]Bradykinin, supplier, Selective, B1, agonists, Receptors, Bradykinin, Tocris Bioscience, Bradykinin Receptor Agonist products
Find multiple products by catalog number
New Products in this Area
Endogenous calcitonin receptor agonist; inhibits bone resorptionSpexin
Potent GAL2/3 agonist; exhibits anxiolytic effects in vivoMM 54
Potent apelin receptor antagonistMSG 606
Potent human MC1 receptor antagonist; also MC3 and MC5 partial agonist
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.