Lys-[Des-Arg9]Bradykinin

Cat. No. 3225

Lys-[Des-Arg9]Bradykinin Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe

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Alternative Name: Des-Arg10-Kallidin

Biological Activity

Endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces peripheral vascular resistance in vivo. 16-fold more potent than [Des-Arg9]-Bradykinin (Cat No. 3005).

Technical Data

M.Wt:
1032.21
Formula:
C50H73N13O11
Sequence:
KRPPGFSPF
Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
71800-36-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Certificate of Analysis / Product Datasheet
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Leeb-Lundberg et al (2005) International union of pharmacology. LV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol.Rev. 57 27. PMID: 15734727.

Regoli et al (2001) Classification of kinin receptors. Biol.Chem. 382 31. PMID: 11258668.

Drapeau et al (1991) Hypotensive effects of Lys-des-Arg9-Bradykinin and metabolically protected agonists of B1 receptors for kinins. J.Pharmacol.Exp.Ther. 259 997. PMID: 1662280.

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Keywords: Lys-[Des-Arg9]Bradykinin, supplier, Selective, B1, agonists, Receptors, Bradykinin, Tocris Bioscience, Bradykinin Receptor Agonist products

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