CGP 36216 hydrochloride

Cat. No. 3219

CGP 36216 hydrochloride C5H14NO2P.HCl [123691-29-2]

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Chemical Name: (3-Aminopropyl)ethylphosphinic acid hydrochloride

Biological Activity

Selective GABAB antagonist. Displays activity at presynaptic receptors; ineffective at GABAB postsynaptic receptors.

Technical Data

M.Wt:
187.6
Formula:
C5H14NO2P.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Desiccate at RT
CAS No:
123691-29-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Ong et al (2001) CGP 36216 is a selective antagonist at GABAB presynaptic receptors in rat brain. Eur.J.Pharmacol. 415 191. PMID: 11274998.

Froestl et al (1995) Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists. J.Med.Chem. 38 3313. PMID: 7650685.

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Keywords: CGP 36216 hydrochloride, supplier, CGP36216, hydrochloride, gabab, antagonists, presynaptic, selective, Tocris Bioscience, GABAB Receptor Antagonist products

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