CGP 36216 hydrochloride
Cat. No. 3219
Chemical Name: (3-Aminopropyl)ethylphosphinic acid hydrochloride
Biological ActivitySelective GABAB antagonist. Displays activity at presynaptic receptors; ineffective at GABAB postsynaptic receptors.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Ong et al (2001) CGP 36216 is a selective antagonist at GABAB presynaptic receptors in rat brain. Eur.J.Pharmacol. 415 191. PMID: 11274998.
Froestl et al (1995) Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists. J.Med.Chem. 38 3313. PMID: 7650685.
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Citations are publications that use Tocris products. Selected citations for CGP 36216 hydrochloride include:
Chen et al (2015) Morphine disinhibits glutamatergic input to VTA dopamine neurons and promotes dopamine neuron excitation. J Neurosci 4. PMID: 26208338.
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Keywords: CGP 36216 hydrochloride, supplier, CGP36216, hydrochloride, gabab, antagonists, presynaptic, selective, Tocris Bioscience, GABAB Receptor Antagonist products
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