Cat. No. 1142
Chemical Name: 3-[(4,5-Dihydro-1H-imidazol-2-yl)me
Biological ActivityPartial α2A adrenoceptor agonist and α1A agonist. Agonist/antagonist activity at 5-HT receptors.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Bayorh et al (1997) Cardiovascular effects of oxymetazoline and UK14,304 in conscious and pithed rats. Clin.Exp.Hypertens. 19 445. PMID: 9140707.
Horie et al (1995) Selectivity of the imidazoline α-adrenoceptor agonists (oxymetazoline and cirazoline) for human cloned α1-adrenoceptor subtypes. Br.J.Pharmacol. 116 1611. PMID: 8564227.
Schoeffter et al (1991) Interaction of the α-adrenoceptor agonist oxymetazoline with serotonin 5-HT1A, 5-HT1B, 5-HT1C and 5-HT1D receptors. Eur.J.Pharmacol. 196 213. PMID: 1678720.
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Selective, high affinity, non-competitive α1A adrenoceptor antagonist
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