Oxymetazoline hydrochloride

Cat. No. 1142

Oxymetazoline hydrochloride C16H24N2O.HCl [2315-02-8]

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Chemical Name: 3-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethyl-phenol hydrochloride

Biological Activity

Partial α2A adrenoceptor agonist and α1A agonist. Agonist/antagonist activity at 5-HT receptors.

Technical Data

M.Wt:
296.84
Formula:
C16H24N2O.HCl
Solubility:
Soluble to 50 mM in water
Purity:
>99 %
Storage:
Store at RT
CAS No:
2315-02-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Bayorh et al (1997) Cardiovascular effects of oxymetazoline and UK14,304 in conscious and pithed rats. Clin.Exp.Hypertens. 19 445. PMID: 9140707.

Horie et al (1995) Selectivity of the imidazoline α-adrenoceptor agonists (oxymetazoline and cirazoline) for human cloned α1-adrenoceptor subtypes. Br.J.Pharmacol. 116 1611. PMID: 8564227.

Schoeffter et al (1991) Interaction of the α-adrenoceptor agonist oxymetazoline with serotonin 5-HT1A, 5-HT1B, 5-HT1C and 5-HT1D receptors. Eur.J.Pharmacol. 196 213. PMID: 1678720.

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