Cat. No. 0329
Alternative Name: (S)-3C4HPG
Biological ActivityMixed group I metabotropic glutamate receptor antagonist and group II mGlu agonist. (R)-3-Carboxy-4-hydroxyphenylglycine (Cat. No. 0328) also available.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Sekiyama et al (1996) Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br.J.Pharmacol. 117 1493. PMID: 8730745.
Hayashi et al (1994) Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor sub-types. J.Neurosci. 14 3370. PMID: 8182479.
Watkins and Collingridge (1994) Phenylglycine derivatives as antagonists of metabotropic glutamate receptors. TiPS 15 333. PMID: 7992387.
Watkins et al (1987) Recent advances in the pharmacology of excitatory amino acids. Excitatory Amino Acid Transmission. Eds. Hicks, Lo 19-26.
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Citations are publications that use Tocris products.
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Keywords: (S)-3-Carboxy-4-hydroxyphenylglycine, supplier, Group, I, antagonists, group, II, agonists, Selective, mGlur, Receptors, mGlu1, mGlu5, mGluR1, mGluR5, Glutamate, Metabotropic, mGlu2, mGlu3, mGluR2, mGluR3, Tocris Bioscience, Glutamate (Metabotropic) Group I Receptor Antagonist products