5-Carboxamidotryptamine maleate

Cat. No. 0458

5-Carboxamidotryptamine maleate C11H13N3O.C4H4O4 [74885-72-6]

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Alternative Names: AH-21467, 5-CT

Biological Activity

5-HT1 agonist with high affinity at 5-HT1A, 5-HT1B , 5-HT1D, 5-ht5 and 5-HT7 receptors.

Technical Data

M.Wt:
319.32
Formula:
C11H13N3O.C4H4O4
Solubility:
Soluble to 100 mM in water
Purity:
>99 %
Storage:
Desiccate at +4°C
CAS No:
74885-72-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

Wood et al (2000) Antagonist activity of meta-chlorophenylpiperazine and partial agonist activity of 8-OH-DPAT at the 5-HT7 receptor. Eur.J.Pharmacol. 396 1. PMID: 10822046.

Nowak et al (1993) [3H]-5-carboxamidotryptamine labels 5HT1D binding sites in bovine substantia nigra. Br.J.Pharmacol. 109 1206. PMID: 8401931.

Beer et al (1992) An investigation of the 5-HT1D receptor binding affinity of 5-hydroxytryptamine, 5-carboxyamidotryptamine and sumatriptan in the central nervous system of seven species. Eur.J.Pharmacol. 213 193. PMID: 1325915.

Zifa and Fillion (1992) 5-Hydroxytryptamine receptors. Pharmacol.Rev. 44 401. PMID: 1359584.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for 5-Carboxamidotryptamine maleate include:

Müller et al (2009) 5-hydroxytryptamine modulates migration, cytokine and chemokine release and T-cell priming capacity of dendritic cells in vitro and in vivo. PLoS One 4 e6453. PMID: 19649285.

Manzke et al (2009) Serotonin targets inhibitory synapses to induce modulation of network functions. Philos Trans R Soc Lond B Biol Sci 364 2589. PMID: 19651659.

Do you know of a great paper that uses 5-Carboxamidotryptamine maleate from Tocris? If so please let us know.

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Keywords: 5-Carboxamidotryptamine maleate, supplier, high, affinity, 5ht5A, 5-HT7, 5-HT1, agonists, Serotonin, Receptors, 5-Hydroxytryptamine, 5-HT, 5-ht5, Non-Selective, AH21467, Tocris Bioscience, Non-selective 5-HT1 Agonist products

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