Cat. No. 0458
Alternative Names: AH-21467, 5-CT
Biological Activity5-HT1 agonist with high affinity at 5-HT1A, 5-HT1B , 5-HT1D, 5-ht5 and 5-HT7 receptors.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Wood et al (2000) Antagonist activity of meta-chlorophenylpiperazine and partial agonist activity of 8-OH-DPAT at the 5-HT7 receptor. Eur.J.Pharmacol. 396 1. PMID: 10822046.
Nowak et al (1993) [3H]-5-carboxamidotryptamine labels 5HT1D binding sites in bovine substantia nigra. Br.J.Pharmacol. 109 1206. PMID: 8401931.
Beer et al (1992) An investigation of the 5-HT1D receptor binding affinity of 5-hydroxytryptamine, 5-carboxyamidotryptamine and sumatriptan in the central nervous system of seven species. Eur.J.Pharmacol. 213 193. PMID: 1325915.
Zifa and Fillion (1992) 5-Hydroxytryptamine receptors. Pharmacol.Rev. 44 401. PMID: 1359584.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products. Selected citations for 5-Carboxamidotryptamine maleate include:
Müller et al (2009) 5-hydroxytryptamine modulates migration, cytokine and chemokine release and T-cell priming capacity of dendritic cells in vitro and in vivo. PLoS One 4 e6453. PMID: 19649285.
Manzke et al (2009) Serotonin targets inhibitory synapses to induce modulation of network functions. Philos Trans R Soc Lond B Biol Sci 364 2589. PMID: 19651659.
Do you know of a great paper that uses 5-Carboxamidotryptamine maleate from Tocris? If so please let us know.
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October 30 - November 3, 2016
Boston, MA, USA