Kifunensine

Cat. No. 3207

Kifunensine C8H12N2O6 [109944-15-2]

Price and Availability

For Kifunensine pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: (5R,6R,7S,8R,8aS)-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione

Biological Activity

Inhibitor of class I α-mannosidases that inhibits glycoprotein processing. Inhibits human endoplasmic reticulum α-1,2-mannosidase I and Golgi Class I mannosidases IA, IB and IC with Ki values of 130 and 23 nM respectively.

Technical Data

M.Wt:
232.19
Formula:
C8H12N2O6
Solubility:
Soluble to 10 mM in water with sonication
Storage:
Store at -20°C
CAS No:
109944-15-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet

Hering et al (2005) A practical synthesis of kifunensine analogues as inhibitors of endoplasmic reticulum α-Mannosidase I. J.Org.Chem. 70 9892. PMID: 16292820.

Elbein et al (1990) Kifunensine, a potent inhibitor of the glycoprotein processing mannosidase I. J.Biol.Chem. 265 1559.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products.

Do you know of a great paper that uses Kifunensine from Tocris? If so please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: Kifunensine, supplier, inhibitors, inhibits, class, I, α-mannosidase, alpha-mannosidases, Glycosylases, Carbohydrate, Metabolism, Tocris Bioscience, Glycosylase Inhibitor products

Quick Order

Find multiple products by catalog number

divider line

New Product Guide

New Product Guide (Spring/Summer 2016)

Our New Product guide highlights over 110 new products added in the first half of 2016. View PDF today.

divider line

New Products in this Area

Adaptaquin

HIF-prolyl hydroxylase-2 (PHD2) inhibitor; antioxidant

pCPA methyl ester hydrochloride

Tryptophan hydroxylase inhibitor

Sign-up for new product e-alerts
divider line

Twitter Updates

Follow @Tocris on Twitter

Follow us on Twitter!

Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.