Cat. No. 1364
Chemical Name: (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-
Biological ActivityPlant-derived alkaloid that binds to tubulin and depolymerizes microtubules.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Bai et al (1996) Identification of cysteine 354 of β-tubulin as part of the binding site for the A ring of colchicine. J.Biol.Chem. 271 12639. PMID: 8647876.
Burns (1992) Analysis of the colchicine-binding site of β-tubulin. FEBS Lett. 297 205. PMID: 1544399.
Hastie (1991) Interactions of colchicine with tubulin. Pharmacol.Ther. 51 377. PMID: 1792241.
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Keywords: Colchicine, supplier, inhibitors, inhibits, tubulin, Tau, Tubulin, Microtubules, Mitosis, Tocris Bioscience, Microtubule products