Camostat mesylate

Cat. No. 3193

Camostat mesylate C20H22N4O5.CH3SO3H [59721-29-8]

Price and Availability

For Camostat mesylate pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneacetic acid 2-(dimethylamino)-2-oxoethyl ester methanesulfonate

Biological Activity

Orally active protease inhibitor. Known to inhibit trypsin and various inflammatory proteases including plasmin, kallikrein and thrombin. Suppresses pancreatitis-induced pain in rats following oral administration.

Technical Data

M.Wt:
494.52
Formula:
C20H22N4O5.CH3SO3H
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>98 %
Storage:
Desiccate at RT
CAS No:
59721-29-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Ishikura et al (2007) The proteinase inhibitor camostat mesilate suppresses pancreatic pain in rodents. Life Sci. 80 1999. PMID: 17433371.

Horiuchi et al (1990) Gabexate and camostat, synthetic proteinase inhibitors, as direct inducing factors of water and bicarbonate secretion in the isolated and blood-perfused dog pancreas. J.Pharmacol.Exp.Ther. 252 320. PMID: 1688943.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for Camostat mesylate include:

Gamble et al (2013) Plasminogen activator inhibitor (PAI)-1 suppresses inhibition of gastric emptying by cholecystokinin (CCK) in mice. Leukemia 185 41518. PMID: 23816469.

Shirato et al (2013) Middle East respiratory syndrome coronavirus infection mediated by the transmembrane serine protease TMPRSS2. J Virol 87 12552. PMID: 24027332.

Kawase et al (2012) Simultaneous treatment of human bronchial epithelial cells with serine and cysteine protease inhibitors prevents severe acute respiratory syndrome coronavirus entry. J Virol 86 6537. PMID: 22496216.

Do you know of a great paper that uses Camostat mesylate from Tocris? If so please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: Camostat mesylate, supplier, Orally, active, protease, inhibitors, inhibits, Proteases, Proteinases, trypsin, plasmin, kallikrein, thrombin, Tocris Bioscience, Other Protease Inhibitor products

Quick Order

Find multiple products by catalog number

divider line

New Product Guide

New Product Guide (Fall/Winter 2016)

Our New Product guide highlights over 100 new products added in the second half of 2016. Request copy or view PDF today.

divider line

New Products in this Area

(R)-MG 132

Potent 20S proteasome inhibitor

Diprotin A

Dipeptidyl peptidase IV (DPP-IV) inhibitor

Acein

High affinity angiotensin-converting enzyme (ACE) ligand

TMI 1

Adam 17 (TACE) and MMP inhibitor; orally bioavailable

Ritonavir

HIV-1 and HIV-2 protease inhibitor

Acetyl Pepstatin

High affinity aspartic protease inhibitor; inhibits HIV-1/2 proteinases

Sign-up for new product e-alerts
divider line

LinkedIn Updates

Follow Tocris on LinkedIn

Follow us on LinkedIn!

Visit our LinkedIn page for the latest Tocris news, events and updates.