Cat. No. 3193
Chemical Name: 4-[[4-[(Aminoiminomethyl)amino]benz
Biological ActivityOrally active protease inhibitor. Known to inhibit trypsin and various inflammatory proteases including plasmin, kallikrein and thrombin. Suppresses pancreatitis-induced pain in rats following oral administration.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Ishikura et al (2007) The proteinase inhibitor camostat mesilate suppresses pancreatic pain in rodents. Life Sci. 80 1999. PMID: 17433371.
Horiuchi et al (1990) Gabexate and camostat, synthetic proteinase inhibitors, as direct inducing factors of water and bicarbonate secretion in the isolated and blood-perfused dog pancreas. J.Pharmacol.Exp.Ther. 252 320. PMID: 1688943.
If you know of a relevant reference for Camostat mesylate please let us know.
Citations are publications that use Tocris products. Selected citations for Camostat mesylate include:
Gamble et al (2013) Plasminogen activator inhibitor (PAI)-1 suppresses inhibition of gastric emptying by cholecystokinin (CCK) in mice. Leukemia 185 41518. PMID: 23816469.
Shirato et al (2013) Middle East respiratory syndrome coronavirus infection mediated by the transmembrane serine protease TMPRSS2. J Virol 87 12552. PMID: 24027332.
Kawase et al (2012) Simultaneous treatment of human bronchial epithelial cells with serine and cysteine protease inhibitors prevents severe acute respiratory syndrome coronavirus entry. J Virol 86 6537. PMID: 22496216.
Do you know of a great paper that uses Camostat mesylate from Tocris? If so please let us know.
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Keywords: Camostat mesylate, supplier, Orally, active, protease, inhibitors, inhibits, Proteases, Proteinases, trypsin, plasmin, kallikrein, thrombin, Tocris Bioscience, Other Protease Inhibitor products
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