Neuropeptide FF

Cat. No. 3137

Neuropeptide FF Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2

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Biological Activity

Endogenous antiopioid peptide and agonist at NPFF1 and NPFF2 receptors (Ki values are 2.82 and 0.21 nM respectively). Exhibits anorexigenic effects following i.c.v. administration.

Technical Data

M.Wt:
1081.28
Formula:
C54H76N14O10
Sequence:
FLFQPQRF

(Modifications: Phe-8 = C-terminal amide)

Solubility:
Soluble to 0.50 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
99566-27-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
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References are publications that support the products' biological activity.

Cline et al (2007) Central neuropeptide FF reduces feed consumption and affects hypothalamic chemistry in chicks. Neuropeptides 41 433. PMID: 17936900.

Gouarderes et al (2007) Functional differences between NPFF1 and NPFF2 receptor coupling: high intrinsic activities of RFamide-related peptides on stimulation of[35S]GTPγS binding. Neuropharmacology 52 376. PMID: 17011599.

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Citations are publications that use Tocris products.

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Keywords: Neuropeptide FF, supplier, Endogenous, NPFF1, NPFF2, agonists, Anti-opioids, NPFFR1, NPFFR2, Receptors, Neuropeptides, FF/AF, NeuropeptideFF, Tocris Bioscience, Neuropeptide FF/AF Receptor Agonist products

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