MG 624

Cat. No. 1356

MG 624 C22H30NOI [77257-42-2]

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Chemical Name: N,N,N-Triethyl-2-[4-(2-phenylethenyl)phenoxy]ethanaminium iodide

Biological Activity

A selective antagonist for neuronal α7 subunit- containing nAChR subtypes. Inhibits α-Bgtx binding to chick α7 and α4β2 subtypes with Ki values of 106 nM and 84 μM respectively.

Technical Data

Soluble to 20 mM in DMSO and to 10 mM in ethanol
>98 %
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
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References are publications that support the products' biological activity.

Maggi et al (1999) Selective effects of a 4-oxystilbene derivative on wild and mutant neuronal chick α7 nicotinic receptor. Br.J.Pharmacol. 126 285. PMID: 10051147.

Gotti et al (1998) 4-Oxystilbene compounds are selective ligands for neuronal nicotinic abungarotoxin receptors. Br.J.Pharmacol. 124 1197. PMID: 9720791.

If you know of a relevant reference for MG 624 please let us know.

Citations are publications that use Tocris products. Selected citations for MG 624 include:

Cassilly et al (2016) SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A. Int J Clin Exp Pathol 11 e0154932. PMID: 27183222.

Do you know of a great paper that uses MG 624 from Tocris? If so please let us know.

View Related Products by Product Action

Keywords: MG 624, supplier, α7, alpha7, neuronal, nicotinic, receptor, antagonist, a7, Receptors, Acetylcholine, nAChR, MG624, Tocris Bioscience, Nicotinic (α7) Receptor Antagonist products

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