1-Deoxymannojirimycin hydrochloride

Cat. No. 1259

1-Deoxymannojirimycin hydrochloride C6H13NO4.HCl [73465-43-7]

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Chemical Name: (2R,3R,4R,5R)-2-(Hydroxymethyl)-3,4,5-piperidinetriol hydrochloride

Biological Activity

Selective inhibitor of α-mannosidase I.

Technical Data

M.Wt:
199.63
Formula:
C6H13NO4.HCl
Solubility:
Soluble to 50 mM in water
Storage:
Desiccate at RT
CAS No:
73465-43-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Certificate of Analysis / Product Datasheet
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Bischoff et al (1986) The use of 1-deoxymannojirimycin to evaluate the role of various α-mannosidases in oligosaccharide processing in intact cells. J.Biol.Chem. 261 4766. PMID: 2937779.

Bischoff and Kornfeld (1984) The effect of 1-deoxymannojirimycin on rat liver α-mannosidases. Biochem.Biophys.Res.Commun. 125 324. PMID: 6239623.

Fuhrmann et al (1984) Novel mannosidase inhibitor blocking conversion of high mannose to complex oligosaccharides. Nature 307 755. PMID: 6230538.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for 1-Deoxymannojirimycin hydrochloride include:

Tareen et al (2014) Design of a novel integration-deficient lentivector technology that incorporates genetic and posttranslational elements to target human dendritic cells. Mol Ther 22 575. PMID: 24419083.

Do you know of a great paper that uses 1-Deoxymannojirimycin hydrochloride from Tocris? If so please let us know.

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Keywords: 1-Deoxymannojirimycin hydrochloride, supplier, α-mannosidase, alpha-mannosidase, I, inhibitors, inhibits, a-Mannosidase, Glycosylases, Carbohydrate, Metabolism, antibiotics, Tocris Bioscience, Glycosylase Inhibitor products

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