Cat. No. 3262
Chemical Name: N-Phenyl-4-(3-phenyl-1,2,4-thiadiaz
Biological ActivitySelective, reversible inhibitor of fatty acid amide hydrolase (FAAH) (IC50 = 12 nM). Brain penetrant and active in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Keith et al (2008) Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amid hydrolase. Bioorg.Med.Chem.Lett. 18 4838. PMID: 18693015.
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Citations are publications that use Tocris products. Selected citations for JNJ 1661010 include:
Stone et al (2012) The cytoprotective effects of oleoylethanolamide in insulin-secreting cells do not require activation of GPR119. Br J Pharmacol 165 2758. PMID: 22029844.
Brown et al (2010) Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines. Carcinogenesis 31 1584. PMID: 20660502.
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Keywords: JNJ 1661010, supplier, Selective, reversible, FAAH, inhibitors, inhibits, Anandamide, Amidase, Fatty, Acid, Amide, Hydrolases, JNJ1661010, Tocris Bioscience, FAAH Inhibitor products
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