FK 409

Cat. No. 3105

FK 409 C8H13N3O4 [138472-01-2]

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Alternative Names: NOR-3, (±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide

Chemical Name: (2E,3E)-4-Ethyl-2-(hydroxyimino)-5-nitro-3-hexenamide

Biological Activity

NO donor; exhibits vasorelaxant (EC50 = 3.9 nM) and antiplatelet activities (IC50 = 4.9 μM). Cell permeable.

Technical Data

Soluble to 100 mM in DMSO and to 100 mM in ethanol
>98 %
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Fukuyama et al (1997) Structure-activity relationships of spontaneous nitric oxide releasers, FK409 and its derivatives. J.Pharmacol.Exp.Ther. 282 236. PMID: 9223559.

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Citations are publications that use Tocris products.

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View Related Products by Product Action

Keywords: FK 409, supplier, FK409, NO, donors, nitric, oxide, vasorelaxant, cell, permeable, Tocris Bioscience, NO Donors / Precursor products

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