Carbenoxolone disodium

Cat. No. 3096

Carbenoxolone disodium C34H48Na2O7 [7421-40-1]

Price and Availability

For Carbenoxolone disodium pricing & availability please select your country from the drop down menu:
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: (3β,20β)-3-(3-Carboxy-1-oxopropoxy)-11-oxoolean-12-en-29-oic acid disodium

Biological Activity

Glucocorticoid that inhibits 11β-hydroxysteroid dehydrogenase (11-HSD) and blocks gap junction communication.

Technical Data

Soluble to 100 mM in water
>98 %
Desiccate at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet

Sagar and Larson (2006) Carbenoxolone inhibits junctional trasnfer and upregulates connexin43 expression by a protein kinase A-dependent pathway. J.Cell.Biochem. 98 1543. PMID: 16552723.

Jellinck et al (1993) Differential inhibition of 11 beta-hydroxysteroid dehydrogenase by carbenoxolone in rat brain regions and peripheral tissues. J.Steroid Biochem.Mol.Biol. 46 209. PMID: 8664169.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for Carbenoxolone disodium include:

Shuhaibar et al (2015) Intercellular signaling via cyclic GMP diffusion through gap junctions restarts meiosis in mouse ovarian follicles. Proc Natl Acad Sci U S A 112 5527. PMID: 25775542.

Do you know of a great paper that uses Carbenoxolone disodium from Tocris? If so please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: Carbenoxolone disodium, supplier, Gap, junction, blockers, inhibitors, inhibits, 11, β-hydroxysteroid, beta-hydroxysteroid, dehydrogenase, gap, Connexins, Channels, Dehydrogenases, Tocris Bioscience, Gap Channel Blocker products

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Product Guide

Our Cancer Research Guide highlights over 750 products for cancer research. Request copy or view PDF today.

divider line

New Products in this Area


Activator of STING-dependent signaling

3',3'-cGAMP sodium salt

STING agonist

2',3'-cGAMP sodium salt

Endogenous high affinity STING agonist

c-Di-AMP sodium salt

Endogenous STING and DDX41 agonist; activates STING-dependent signaling

Sign-up for new product e-alerts
divider line

Bio-Techne Events

IVBM 2016

IVBM 2016

October 30 - November 3, 2016

Boston, MA, USA

Booth: 2