Lorazepam

Cat. No. 3087

Lorazepam C15H10Cl2N2O2 [846-49-1]

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Chemical Name: 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepine-2-one

Biological Activity

Ligand at the GABAA receptor benzodiazepine modulatory site. Anxiolytic, anticonvulsant and sedative/hypnotic agent.

Technical Data

M.Wt:
321.16
Formula:
C15H10Cl2N2O2
Solubility:
Soluble to 100 mM in DMSO and to 40 mM in ethanol
Storage:
Store at RT
CAS No:
846-49-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Bonavita et al (2002) Tolerance to the sedative effect of lorazepam correlates with a diminution in cortical release and affinity for glutamate. Neuropharmacol. 42 619.

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Keywords: Lorazepam, supplier, Acts, benzodiazepine, modulatory, site, GABAA, Receptors, Tocris Bioscience, GABAA Receptor Benzodiazepine products

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