DMCM hydrochloride

Cat. No. 3083

DMCM hydrochloride C17H18N2O4.HCl [1215833-62-7]

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Chemical Name: 4-Ethyl-6,7-dimethoxy-9H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester hydrochloride

Biological Activity

Benzodiazepine inverse agonist that displays anxiogenic and potent convulsant activity.

Technical Data

M.Wt:
350.8
Formula:
C17H18N2O4.HCl
Solubility:
Soluble to 100 mM in water and to 50 mM in DMSO
Purity:
>98 %
Storage:
Desiccate at RT
CAS No:
1215833-62-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Conto et al (2005) Behavioral differences between subgroups of rats with high and low threshold to clonic convulsions induced by DMCM, a benzodiazepine inverse agonist. Pharmacol.Biochem.Behav. 82 417. PMID: 16297441.

Sieve et al (2001) Pain and negative affect: evidence the inverse benzodiazepine agonist DMCM inhibits pain and learning in rats. Psychopharmacol. 153 180.

Petersen (1983) DMCM: a potent convusive benzodiazepine receptor ligand. Eur.J.Pharmacol. 94 117. PMID: 6317396.

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Keywords: DMCM hydrochloride, supplier, Benzodiazepine, inverse, agonists, GABAA, Receptors, Tocris Bioscience, GABAA Receptor Benzodiazepine products

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