L-NIL hydrochloride

Cat. No. 1139

L-NIL hydrochloride C8H17N3O2.HCl [150403-89-7]

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Chemical Name: N6-(1-Iminoethyl)-L-lysine hydrochloride

Biological Activity

A selective inhibitor of inducible nitric oxide synthase (IC50 = 3.3 μM).

Technical Data

M.Wt:
223.7
Formula:
C8H17N3O2.HCl
Solubility:
Soluble to 100 mM in water
Storage:
Desiccate at -20°C
CAS No:
150403-89-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

Connor et al (1995) Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase. Eur.J.Pharmacol. 273 15. PMID: 7537678.

Moore et al (1994) L-N6-(1-Iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase. J.Med.Chem. 37 3886. PMID: 7525961.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for L-NIL hydrochloride include:

Elks et al (2013) Hypoxia inducible factor signaling modulates susceptibility to mycobacterial infection via a nitric oxide dependent mechanism. PLoS Pathog 9 e1003789. PMID: 24367256.

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Keywords: L-NIL hydrochloride, supplier, Selective, iNOS, inhibitor, Nitric, Oxide, Signaling, Signalling, Inducible, NO, Synthases, Tocris Bioscience, iNOS Inhibitor products

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