Cat. No. 1139
Chemical Name: N6-(1-Iminoethyl)-L-lysine hydrochloride
Biological ActivityA selective inhibitor of inducible nitric oxide synthase (IC50 = 3.3 μM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Connor et al (1995) Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase. Eur.J.Pharmacol. 273 15. PMID: 7537678.
Moore et al (1994) L-N6-(1-Iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase. J.Med.Chem. 37 3886. PMID: 7525961.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products. Selected citations for L-NIL hydrochloride include:
Elks et al (2013) Hypoxia inducible factor signaling modulates susceptibility to mycobacterial infection via a nitric oxide dependent mechanism. PLoS Pathog 9 e1003789. PMID: 24367256.
Do you know of a great paper that uses L-NIL hydrochloride from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: L-NIL hydrochloride, supplier, Selective, iNOS, inhibitors, inhibits, Nitric, Oxide, Signaling, Signalling, Inducible, NO, Synthases, Tocris Bioscience, iNOS Inhibitor products
Find multiple products by catalog number
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.