BNTX maleate

Cat. No. 0899

BNTX maleate C27H27NO4.C4H4O4 [864461-31-4]

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Chemical Name: 7-Benzylidenenaltrexone maleate

Biological Activity

Standard selective δ1 opioid receptor antagonist. Also inhibits neurogenic ion transport mediated by a putative novel opioid receptor in porcine ileal mucosa.

Technical Data

Soluble to 100 mM in DMSO and to 10 mM in water with gentle warming
>99 %
Desiccate at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
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References are publications that support the products' biological activity.

Poonyachoti et al (2001) Pharmacological evidence for a 7-benzylidenenaltrexone-preferring opioid receptor mediating the inhibitory actions of peptidic δ- and μ-opioid agonists on neurogenic ion transport in porcine ileal mucosa. J.Pharmacol.Exp.Ther. 297 672. PMID: 11303057.

Hammond et al (1995) Antinociception and d-1 opioid receptors in the rat spinal cord: studies with intrathecal 7-benzylidenenaltrexone. J.Pharmacol.Exp.Ther. 274 1317. PMID: 7562504.

Portoghese et al (1992) A δ1-opioid receptor antagonist: 7-benzylidenenaltrexone. Eur.J.Pharmacol. 218 195. PMID: 1327826.

If you know of a relevant reference for BNTX maleate please let us know.

Citations are publications that use Tocris products. Selected citations for BNTX maleate include:

Gomes et al (2000) Heterodimerization of μ and δ opioid receptors: A role in opiate synergy. J Cereb Blood Flow Metab 20 RC110. PMID: 11069979.

Do you know of a great paper that uses BNTX maleate from Tocris? If so please let us know.

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Keywords: BNTX maleate, supplier, δ1-opioid, delta1-opioid, selective, antagonists, DOP, Receptors, OP1, Tocris Bioscience, δ Opioid Receptor Antagonist products

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