Cat. No. 0767
Chemical Name: 4-(2-Benzylphenoxy)-N-methylbutylam
Biological ActivityAntidepressant MAO inhibitor. Reverses catalepsy induced by tetrabenazine in mice and increases locomotor activity in MPTP-treated marmosets.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Nomoto et al (1994) Effects of bifemelane on parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the common marmoset. Neurosci.Lett. 178 95. PMID: 7816348.
Naoi et al (1988) 4-(o-benzylphenoxy)-N-methylbutylamine (bifemelane) and other 4-(o-benzylphenoxy)-N-methylalkylamines as new inhibitors of type A and B monoamine oxidase. J.Neurochem. 50 243. PMID: 3335842.
Tobe et al (1981) Pharmacological evaluation of 2-(4-methylaminobutoxy)diphenylmethane hydrochloride (MCl-2016), a new psychotropic drug with antidepressant activity. Arzneimittelforschung 31 1278. PMID: 7197535.
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Keywords: Bifemelane hydrochloride, supplier, MAO-A, MAO-B, inhibitors, inhibits, Monoamine, oxygenases, Oxidases, Tocris Bioscience, Monoamine Oxidase Inhibitor products