Bifemelane hydrochloride

Cat. No. 0767

Bifemelane hydrochloride C18H23NO.HCl [62232-46-6]

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Chemical Name: 4-(2-Benzylphenoxy)-N-methylbutylamine hydrochloride

Biological Activity

Antidepressant MAO inhibitor. Reverses catalepsy induced by tetrabenazine in mice and increases locomotor activity in MPTP-treated marmosets.

Technical Data

M.Wt:
305.84
Formula:
C18H23NO.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Desiccate at RT
CAS No:
62232-46-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

Nomoto et al (1994) Effects of bifemelane on parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the common marmoset. Neurosci.Lett. 178 95. PMID: 7816348.

Naoi et al (1988) 4-(o-benzylphenoxy)-N-methylbutylamine (bifemelane) and other 4-(o-benzylphenoxy)-N-methylalkylamines as new inhibitors of type A and B monoamine oxidase. J.Neurochem. 50 243. PMID: 3335842.

Tobe et al (1981) Pharmacological evaluation of 2-(4-methylaminobutoxy)diphenylmethane hydrochloride (MCl-2016), a new psychotropic drug with antidepressant activity. Arzneimittelforschung 31 1278. PMID: 7197535.

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Keywords: Bifemelane hydrochloride, supplier, MAO-A, MAO-B, inhibitors, inhibits, Monoamine, oxygenases, Oxidases, Tocris Bioscience, Monoamine Oxidase Inhibitor products

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