Betaxolol hydrochloride

Cat. No. 0906

Betaxolol hydrochloride C18H29NO3.HCl [63659-19-8]

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Chemical Name: 1-[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]-3-isopropylamino-2-propanol hydrochloride

Biological Activity

Selective β1-adrenoceptor antagonist.

Technical Data

M.Wt:
343.89
Formula:
C18H29NO3.HCl
Solubility:
Soluble to 50 mM in water
Purity:
>99 %
Storage:
Store at RT
CAS No:
63659-19-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Setoguchi et al (1995) Inhibitory action of betaxolol, a β1-selective adrenoceptor antagonist, on voltage-dependent calcium channels in guinea pig artery and vein. Br.J.Pharmacol. 115 198. PMID: 7647977.

Satoh et al (1993) The affinity of betaxolol, a β1-adrenoceptor-selective blocking agent, for β-adrenoceptors in the bovine trachea and heart Br.J.Pharmacol. 108 484. PMID: 8383566.

Beresford and Heel (1986) Betaxolol. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in hypertension. Drugs 31 6. PMID: 2866947.

Merck Index 12 1229.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for Betaxolol hydrochloride include:

Littmann et al (2015) Recruitment of β-arrestin 1 and 2 to the β2-adrenoceptor: analysis of 65 ligands. Cardiovasc Res 355 183. PMID: 26306764.

Meitzen et al (2011) β1-Adrenergic receptors activate two distinct signaling pathways in striatal neurons. J Neurochem 116 984. PMID: 21143600.

Do you know of a great paper that uses Betaxolol hydrochloride from Tocris? If so please let us know.

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