Cat. No. 1410
Chemical Name: (4bS,8R,8aS,14bR)-5,6,7,8,14,14b-He
Biological ActivityPotent and highly selective non-peptide δ receptor antagonist (Ki values are 4.7, 3800 and 7900 nM for δ, κ and μ receptors respectively). More selective than naltrindole (Cat. No. 0740).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
McLamore et al (2001) Effect of N-alkyl and N-alkenyl substituents in noroxymorphindole, 17-substituted-6,7-dehydro-4,5α-epoxy-3,14-dihydroxy-6,7:2 ',3 '-indolomorphinans, on opioid receptor affinity, selectivity, and efficacy. J.Med.Chem. 44 1471. PMID: 11311071.
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Citations are publications that use Tocris products. Selected citations for SDM25N hydrochloride include:
Ong et al (2015) Prolonged morphine treatment alters δ opioid receptor post-internalization trafficking. Br J Pharmacol 172 615. PMID: 24819092.
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Keywords: SDM25N hydrochloride, supplier, Potent, selective, non-peptide, δ-opioid, delta-opioid, antagonist, DOP, Receptors, OP1, Tocris Bioscience, δ Opioid Receptor Antagonist products
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