Cat. No. 0424
Chemical Name: N,N'-[(3,6-Dioxo-1,4-cyclohexadiene-
Biological ActivityNicotinic antagonist, ganglion blocker. Activates single channels but blocks open channels at nicotinic receptors.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Pereira et al (1993) Identification and functional characterization of a new agonist site on nicotinic acetylcholine receptors of cultured hippocampal neurons. J.Pharmacol.Exp.Ther. 265 1474. PMID: 8510023.
Bowman and Webb (1972) Neuromuscular blocking and ganglia blocking activities of some acetylcholine antagonists in the cat. J.Pharm.Pharmacol. 24 762. PMID: 4403972.
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Keywords: Benzoquinonium dibromide, supplier, Nicotinic, antagonists, Acetylcholine, Receptors, Non-Selective, Subtypes, nAChR, Tocris Bioscience, Nicotinic Receptor (Non-selective) Antagonist products
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Potent positive allosteric modulator of α4β2 nAChRs; also inhibitor of (α4)2(β2)3, muscle-type and Torpedo nAChRs
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